
Pills and drugs for depression
Content:
- Antipsychotics
- Antidepressants
- Tranquilizers
- Nootropics
- Sedatives
To get out of depression, 5 groups of drugs are used, namely: neuroleptics, antidepressants, tranquilizers, nootropics and sedatives. About each of the categories presented below.
Antipsychotics

Used in psychoses, neuroses, insomnia and depression. The drugs in this group make it possible to cope with anxiety and anxiety, obsession and agitation.
Antipsychotics include: "Aminazin", "Zyprexa", "Mazheptil", "Leponex":
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"Aminazine" is administered intravenously or intramuscularly. The advantage of the drug is that it can be used even with acute arousal, but it has certain contraindications and side effects. So, "Aminazin" is unacceptable to use for liver and kidney diseases, severe hypotension, stomach diseases. The side effects of this neuroleptic are also diverse: the urge to nausea and vomiting, parkinsonism, allergic reactions on the skin.
- "Zyprexa" - which is available in the form of tablets. Allowed for use by pregnant women and even during the lactation period. Contraindication - increased sensitivity to drug components. Causes minor side effects such as drowsiness. May interact with other drugs - levodopa, dopamine agonists.
- "Mazheptil" is produced both as tablets and in the form of solutions for intramuscular injections. Speaking of contraindications, it should be noted agranulocytosis of the toxic type, angle-closure glaucoma, prostate adenoma and any stage of parkinsonism. In small doses, use during pregnancy is allowed. The remedy has a large number of contraindications: from apathy to an increase in body index and jaundice.
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"Leponex" - available in the form of a solution for injection and tablets. When interacting with clazopine, constant dose adjustment is required. It is permissible for people over 65 years of age. You should carefully monitor the body's reactions to the remedy, since the likelihood of developing psychosis and other complications is high.
Antidepressants
They help not only to calm down, but also to activate the nervous system. It is advisable to use only in case of strong excitement, because there is a high probability of addiction.
Antidepressants include:
- "Lerivon" is available in the form of tablets and is characterized by a quick effect due to absorption in the gastrointestinal tract. It is not recommended for use in case of manic syndrome and even more severe disorders. It is strictly contraindicated in pregnancy and breastfeeding. Incompatible with MAO inhibitors, and also has a large number of side effects;
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"Fluoxetine" is a powdery remedy that begins to act after 2-3 weeks, gradually relieving depression. Has a number of serious contraindications (glaucoma, hypersensitivity and others), as well as restrictions in terms of use (cirrhosis of the liver, heart attack). It is characterized by many side effects and is not compatible with MAO inhibitors;
- "Prozac" - is available in capsules and soluble tablets. Contraindicated in hypersensitivity, not recommended for use during pregnancy and lactation period. Side effects appear mainly at the very beginning of using the product - anxiety, small rashes on the skin, as well as headache and nausea. Changes the ratio of lithium in the blood. A fairly frequent dose adjustment is required (preferably once every 1.5-2 months).
Tranquilizers

Drugs related to tranquilizers are highly addictive, therefore strict medical supervision is indicated.
This category includes "Phenibut", "Phenazepam", "Elenium", "Temazepam":
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Phenibut is available in the form of tablets. It has a number of contraindications: pregnancy, renal failure, individual intolerance to the Phenibut components. It enhances the effects of many drugs, from anxiolytic to anticonvulsant. With prolonged use, it is necessary to monitor the status and composition of the blood, as well as the indicators of liver function.
- "Phenazepam" is available in the form of tablets and is associated with a large number of contraindications. Therefore, it should be taken with extreme caution, starting with the smallest doses. The maximum dose within 24 hours is 10 mg, otherwise an overdose occurs: depression of consciousness, a decrease in blood pressure and even coma. Not recommended for people under 18 years of age.
- "Elenium" - is a dragee. Contraindicated with increased sensitivity to components, pregnancy, glaucoma. During the first doses, side effects are likely, which decrease as the body gets used to it. In case of problems with the kidneys and liver, "Elenium" is used with extreme caution, as well as at the age of 65 years. When signs of addiction become noticeable, you should stop taking the drug. This should be done gradually.
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Temazepam is a powdery product that is poorly soluble in water. This is the most powerful of the tranquilizers, which is unacceptable for pregnant women. Has a number of other contraindications, including age under 18 years. Side effects are possible, both from the nervous system and from the digestive tract. The dosage is always set individually and requires frequent adjustments.
On the subject: 3 medicinal plants to help with depression
Nootropics
The most harmless group of drugs that can be used in depression. These include tools such as:
- "Glycine" - tablets that easily get into the vast majority of biological fluids. They can not only be drunk, but also made into a powdery state. Contraindicated in case of hypersensitivity, side reactions are also likely. Reduces the severity of some antidepressants. Available without a prescription, but use outside of medical supervision is highly undesirable.
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"Quattrex" - capsules, which are indicated for acute renal failure, hypersensitivity and children under 11 years of age. It should be used with caution in the context of problems with the gastrointestinal tract, constant monitoring of the composition of blood and liver enzymes is necessary. The tool is capable of affecting the reaction rate, and therefore the use when driving transport and working with mechanisms is prohibited.
Sedatives

The last group is light drugs, which are indicated for use in depression and weakening of the central nervous system. These include drugs such as Valemidin, Novo-Passit. The first one is alcohol-based drops. They help restore sleep, cope with depression and cardiovascular neuroses. There are many contraindications: from age under 18 to problems with the central nervous system and liver function.
Sedatives include:
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"Valemidin" is most often used as an additional agent, since it enhances the effect of antidepressants and nootropics. Allergic reactions are possible, and with prolonged use, dryness of the oral mucosa is noted. The course of treatment should be 10 to 15 days. The cycle can be repeated no earlier than after 30-40 days and only on the recommendation of a doctor.
- Novo-Passit is available in the form of solutions and tablets. It has a number of contraindications: myasthenia gravis, age up to 12 years, hypersensitivity. In addition, it should be used with caution in case of problems with the gastrointestinal tract, liver, depression, which is accompanied by alcoholism, brain injury. The drug is well tolerated, but in rare cases, allergies, fatigue, and decreased concentration are possible.
The tool enhances the effect of other antidepressants, and therefore requires consultation with a specialist and periodic dose adjustments. Within the first 7 days, the condition should improve markedly. If this does not happen, it is recommended to either increase the dosage or abandon Novo-Passit. All this should be done only with the agreement of the attending physician.

Author of the article: Alekseeva Maria Yurievna | Therapist
Education: From 2010 to 2016 Practitioner of the therapeutic hospital of the central medical-sanitary unit No. 21, city of elektrostal. Since 2016 she has been working in the diagnostic center No. 3.
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