Antihypoxants - What Are They? List Of Drugs

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Antihypoxants - What Are They? List Of Drugs
Antihypoxants - What Are They? List Of Drugs
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List of antihypoxants for hypoxia

List of antihypoxants
List of antihypoxants

Most hospital patients undergoing therapy for various chronic pathologies note that in addition to the main treatment, they are often prescribed antihypoxants and antioxidants. Also, after discharge from the hospital, doctors strongly recommend taking a course of vitamins that have an antioxidant effect. This allows the body to quickly cope with the disease. Antioxidants are often prescribed to women in position, children in puberty, patients with immunodeficiency states, people who are experiencing increased physical activity.

Content:

  • Hypoxic syndrome - what is it?
  • Antihypoxic drugs
  • Dangers of free radicals to health
  • Antioxidant drugs
  • Antioxidants and antihypoxants: what's the difference?

Hypoxic syndrome - what is it?

Hypoxic syndrome
Hypoxic syndrome

Hypoxic syndrome, as an independent disorder in tissue cells, is not often observed. However, it is associated with most diseases, regardless of their origin. With hypoxia, it is much more difficult for the body to deal with the existing pathology.

If the tissues of organs do not receive enough oxygen, this is accompanied by the following disorders:

  • Cells are not able to release enough energy for the body.
  • There is an increase in the processes of free oxidation of radicals.
  • Healthy cells are destroyed faster.

Therefore, doctors, in order to restore the normal functioning of cells, in order for them to be able to perceive and utilize oxygen, prescribe antihypoxants to patients.

The indications for their use are the following conditions:

  • Shock, regardless of the nature of its origin.
  • Heart failure.
  • Coma.
  • Collapse.
  • Pregnancy, accompanied by fetal hypoxia. Antihypoxants are prescribed both during gestation and during childbirth.
  • Anemia.
  • Intoxication of the body, withdrawal symptoms.
  • Massive surgical interventions.

Antihypoxants are drugs that are aimed at preventing tissue hypoxia in the human body.

Antihypoxic drugs

Antihypoxic drugs
Antihypoxic drugs

The majority of patients among themselves call antihypoxants vascular drugs. This is because they are widely used in the treatment of people suffering from cardiovascular diseases. In fact, all drugs that cardiologists prescribe to their patients have an antihypoxic effect to one degree or another.

Among such medicines:

  • Vinpocetine and Cavinton. These medicines are made from herbal raw materials. The main active ingredient is vincamine. Both Vinpocetine and Cavinton have a minimal set of contraindications, but give an excellent effect in hypoxia. Their reception allows you to normalize metabolic processes in the brain tissues, improve their blood supply.
  • Riboxin. This drug is prescribed when there is a need to normalize metabolic processes in the heart muscle. Riboxin prevents the development of hypoxia.
  • Piracetam. This drug is aimed at improving the blood supply to the brain, at increasing the rate of metabolic processes in its tissues. The drug allows you to prevent the effects of brain hypoxia, improves attention, memory, increases mental performance. It is prescribed to their patients by narcologists, psychotherapists, pediatricians.
  • Mildronate (meldonium). This drug contains in its composition an active active substance, which is in every cell of the human body. It's called gamma-butyrobetaine. Reception of Meldonium allows you to normalize metabolic processes in the tissues of organs, to ensure an adequate supply of oxygen to them. Mildronate is now known all over the world as a drug from the doping group, since, due to its presence in the blood, many eminent athletes were deprived of the opportunity to participate in competitions.

  • Inosine. The action of this drug is aimed at starting the enzymes involved in the Krebs cycle. The drug allows you to normalize metabolic processes in the tissues of the heart muscle, increase the body's endurance, and also stimulate its immune forces.
  • Cytochrome C. This drug is prescribed to children during the neonatal period who have suffered from hypoxia caused by suffocation. Also, its reception is indicated for patients with heart failure, asthmatics, people suffering from coronary artery disease.
  • Phezam. This drug is one of the potent drugs in its group of antihypoxants, which is due to its combined composition.
  • Trimetazidine. The drug allows you to improve metabolic processes in the cells that form the basis of the myocardium, normalizes the energy balance in them. Thanks to the intake of Trimetazidine, it is possible to normalize the pressure indicators, increase the body's susceptibility to power and mental stress.

It should be understood that this is not a complete list of drugs from the group of antihypoxants. Moreover, many of the listed drugs have several more dosage forms.

So, Vinpocetine can be found in tablets:

  • Vinpocetine Forte.
  • Vinpocetine.
  • Vinpocetine SAR.

It is produced in the form of an aerosol and is called Vinpocetine AKOS.

You can also find Vinpocetine in the form of a concentrate, from which solutions for infusion are prepared, these are:

  • Vinpocetine SAR.
  • Vinpocetine AKOS.
  • Vinpocetine ESCOM.

Riboxin Ferein and Riboxin Lect are tablet forms of Riboxin. It can also be found in a solution intended for intravenous administration. The drug in this case will be called Riboxin bufus.

Also, nasal drops called Semax are referred to the group of antihypoxants. They have antioxidant properties and a capillary-protective effect. This also includes the drug Solcoseryl, which is available in the form of a gel and in the form of an ointment. This medicinal substance has not only an antihypoxic effect, but also promotes the speedy healing of tissues.

All of these drugs have an antihypoxic effect, but they are also capable of having an antioxidant effect on the body. Therefore, if in other medical sources these funds are included in the list of antioxidant products, you should not be surprised.

Dangers of free radicals to health

Many people know that free radicals are dangerous to health. However, most of them still do not have a clear understanding of what exactly they are. Free radicals are particles that are charged with a free electron. They are in search of a second electron and seek to "take away" it from a healthy cell of the human body. If they succeed, then they damage this cell, causing damage to it. As a result, it can no longer perform the functions that are entrusted to it. Sometimes free radicals are able to launch a whole chain of reactions, which the body cannot stop on its own.

The danger of the free
The danger of the free

You also need to understand that small amounts of free radicals are still needed by the body. With their help, it fights against pathogenic microorganisms and prevents the formation of cancer cells.

Free radicals are formed in the body as a result of a cascade of reactions aimed at breaking down food and utilizing oxygen.

If there are too many of them, then this contributes to the following pathological processes:

  • The cells of the body are damaged and die.
  • Immune powers are weakened.
  • The body undergoes premature aging.
  • Cells undergo mutations.
  • Cancerous tumors develop.

Free radicals are activated at a time when there is a deterioration in the body's defenses. Sometimes they are capable of causing irreparable harm to him.

Taking antioxidants helps fight the excessive formation of free radicals in the body.

The danger of the free
The danger of the free

Antioxidants donate their free electrons to radicals, thereby minimizing their harmful effects.

Antioxidant drugs

There is no doubt that those antioxidants obtained from natural sources, that is, from food entering the body, have the maximum antioxidant effect.

Foods containing antioxidants:

  • Peanuts, asparagus, corn, and peas contain Alpha-Tocopherol Acetate or Vitamin E.
  • Sauerkraut, bell peppers and cranberries contain a lot of vitamin C (ascorbic acid).
  • Spinach, carrots and broccoli are high in provitamin A (beta-carotene).

To stop the processes of early aging of the body, you can eat foods fortified with selenium. To do this, the menu should contain pistachios, coconuts, garlic. Selenium helps to increase the body's resistance, destroys free radicals, and has an anti-inflammatory effect. Selenium is the # 1 antioxidant in the fight against cancer. However, despite such an impressive list of merits, selenium can be harmful to the body. This happens if a person takes it in excess. If selenium enters the body only with food, then an overdose is unlikely, but when replenishing its reserves with the help of other sources, the threat of damage to health becomes quite real.

Antioxidant drugs
Antioxidant drugs

On sale you can find antioxidant preparations, which are represented by multivitamin complexes. For example, these include the drug Antioxicaps. The majority of complexes include vitamins C, A and E. They also contain some chemical elements: selenium, zinc, iron or iodine.

Antioxidants and antihypoxants: what's the difference?

what is the difference
what is the difference

Both antioxidants and antihypoxants are designed to solve a single problem: to help the body get out of a pathological state, to prevent the consequences of tissue cell destruction. Therefore, these drugs are often prescribed in a single regimen. They resist the pathogenic effects of radicals on the body, do not allow the fats that make up the cell membrane to be oxidized, contribute to the normal absorption of oxygen by cells, and ensure the normal functioning of organs under conditions of hypoxia.

Antioxidants and antihypoxants are prescribed in the following cases:

  • Ischemic heart disease.
  • Myocardial infarction.
  • Hemorrhagic and ischemic stroke.
  • Cardialgia against the background of hormonal imbalance.
  • Circulatory disorders of various organs.
  • Atherosclerosis of the vessels.
  • Diabetes mellitus, complicated by vascular pathologies.
  • Sepsis.
  • Burns, trauma, blood loss.
  • Extreme sports.
  • Diseases of the respiratory system of a chronic course.

These drugs are prescribed to increase immunity in various diseases, using them in a complex therapeutic regimen. Therefore, they are so widespread in medical practice.

Antioxidants, as well as antihypoxants, prevent hypoxia from causing serious harm to human health. In turn, antihypoxants resist the damaging effects of free radicals on healthy cells in the body. Therefore, there are drugs that are included in the group of antihypoxant and antioxidant drugs.

These include:

  • Actovegin. It accelerates metabolic processes in tissues, promotes their regeneration, improves their respiration and nutrition.
  • Sodium polyhydroxyphenylene thiosulfate. This drug has a pronounced antihypoxic effect, promotes normal respiration of tissue cells, enhances physical endurance and emotional stability.
  • Ethylthiobenzimidazole hydrobromide. This drug supports the performance of organs and tissues during hypoxia of the body, increases its defenses. The person becomes more able-bodied, hardy, attentive.
  • Emoxipin. Prevents the negative effects of free radicals on the body, prevents them from damaging healthy cells. Supports the functioning of the body during hypoxia.
  • Probucol. This drug helps to normalize fat metabolism in the body, has an antioxidant effect.
  • Ethylmethylhydroxypyridine succinate. The drug does not allow free radicals to damage healthy cells of the body, has a nootropic effect, and is used as an antihypoxic agent.

The drugs that have been described above can also be attributed to this group, since they have both the effect of antihypoxants and antioxidants. However, you need to understand that although these drugs are available without a prescription, they need to be prescribed by a doctor. All of them have both contraindications and side effects, so self-medication is unacceptable.

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Author of the article: Alekseeva Maria Yurievna | Therapist

Education: From 2010 to 2016 Practitioner of the therapeutic hospital of the central medical-sanitary unit No. 21, city of elektrostal. Since 2016 she has been working in the diagnostic center No. 3.

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