2024 Author: Josephine Shorter | [email protected]. Last modified: 2023-12-16 21:43
Effective suppositories for thrush
Suppositories, or suppositories, are used for local treatment of vaginal thrush in women, to reduce the intensity of symptoms of the disease. Their action is based on the penetration of the active substance into the vaginal mucosa. This reduces tissue inflammation, the causative agent of candidiasis dies.
Antifungal drugs used in modern gynecology are available in various forms - topical agents (creams, suppositories) and drugs taken orally (tablets, capsules). Oral preparations are most often used in the treatment of complex forms of candidiasis, with frequent relapses and complications.
The most effective are suppositories for thrush, acting on a type of fungus that is sensitive to them. The resistance and sensitivity of the fungus is determined as a result of bacterial culture, separated from the vagina. In the chronic form of thrush with frequent relapses, its treatment may not be effective due to the developed resistance of the fungus to drugs.
As a complex drug for the local treatment of infectious diseases of the female genital organs, including vaginal candidiasis, gynecologists use Macmiror® Complex. Its antifungal effect is due to the combined action of two components - Nystatin and Nifuratel, where the latter, having its own antifungal effect, significantly enhances the antifungal effect of the former. The result of this dual synergy of the components is that Macmiror® Complex has such a potent antifungal effect, far superior to the antifungal effect of pure Nystatin. The drug is available in two dosage forms for vaginal use (vaginal capsules and cream) and has a wide spectrum of action against pathogenic flora,does not suppress the physiological flora and creates the prerequisites for the restoration of normobiocenosis, thereby reducing the risk of a relapse of the disease.
Self-medication for thrush is fraught with its transition to a chronic form, a violation of the balance of the vaginal microflora. If a woman suffering from thrush uses douching, the disease progresses even more, the composition of the vaginal microflora does not change for the better. The tactics of treating vaginal candidiasis is determined by the doctor. He assesses the patient's state of health, the clinical picture of the disease, the sensitivity of the pathogen, and prescribes a course of treatment. The criterion of cure, even in the absence of thrush symptoms, is a negative analysis for the presence of fungi within 3 months after the end of treatment.
Content:
- Rules for the use of suppositories against thrush
Effective suppositories for thrush in 1 day
- Zalain
- Lomexin
Suppositories for 3 days of treatment
- Livarol and ketoconazole
- Pimafucin
- Econazole
The best suppositories for thrush with course treatment
- Irunin and itraconazole
- Macmiror complex
- Miconazole
- Fluomisan
Cheap candles for thrush
- Clotrimazole
- Nystatin
- Iodoxide
- Pros and cons of using suppositories for thrush
- Candles from thrush during pregnancy
- Vaginal creams as a complementary treatment
Rules for the use of suppositories against thrush
Treatment of a sexual partner is a prerequisite for complete recovery, since a man can be a carrier of candidiasis and transfer it in a latent (hidden) form. If the permanent sexual partner is not treated, the woman will receive a new portion of the fungus at the first unprotected intercourse.
During treatment, sexual intercourse is prohibited, in extreme cases, you need to use condoms. To improve the absorption of the active substance of suppositories, it is recommended that the suppositories be inserted as deep as possible into the vagina.
In case of relapses of thrush, the possible causes of its occurrence should be analyzed during the medical consultation. If the risk factors are not eliminated, candidiasis will occur regularly.
In some cases, candidiasis becomes an indicator of the addition of other infections - gonorrhea, trichomoniasis, chlamydia, mycoplasmosis, bacterial vaginosis, gardnerellosis (a characteristic symptom is discharge with the smell of stale fish).
The course of treatment of a fresh disease without complications can be limited to the use of one suppository, while in the chronic course of thrush, a multi-stage complex treatment may be required.
- Suppositories are not used during menstruation, with the exception of Sertaconazole (Zalain) and Povidone-Iodine (Iodoxide, Betadine).
- Lomeksin, Zalain are used once.
- 3 suppositories each - Pimafucin, Livarol, Gino-pevaril (Econazole).
- From 5 to 14 suppositories - Iodoxide, Irunin, Macmiror, Nystatin (Terzhinan and Polygynax), Clotrimazole, Miconazole (Ginesol).
Additionally, you should carefully observe intimate hygiene, do not wear synthetic underwear, do not use scented pads or toilet paper with perfume, cosmetics for intimate hygiene.
The duration of the course of treatment, the effectiveness and contraindications to the use of suppositories from thrush depend on their composition and concentration of the active substance. Any medications for the treatment of candidiasis should be taken as directed by a doctor, otherwise there is a high risk of side effects.
Effective suppositories for thrush in 1 day
Zalain
Package price with 1 suppository - from 600 rubles.
The active ingredient of the drug Zalain is a derivative of Imizadol and Benzothiophene.
Use during pregnancy: since the drug is used once, and Zalain does not act systemically, in each case, the possible benefits for the woman and the risk to the health of the fetus or infant (when used during lactation) are analyzed. There are no data confirmed by studies on the harm of the drug for pregnant and lactating women.
Contraindications: hypersensitivity to the components of the suppositories.
Side effects: itching and burning in the vagina (do not require discontinuation of the drug), allergic manifestations.
Method of application: the suppository is inserted into the vagina at night once, while the symptoms of thrush persist, it can be re-injected after 7 days. Before starting treatment, it is recommended to conduct an intimate toilet of the external genital organs with soap with a neutral reaction. Suppositories are also used during menstruation.
Advantages and disadvantages: positive properties of the drug - the possibility of a single administration, effectiveness, use throughout the menstrual cycle, disadvantage - high cost.
Lomexin
Lomexin (Fenticonazole), price for 680 r for 2 vaginal capsules.
Contraindications: hypersensitivity, menstruation, pregnancy.
Side effects: slight irritation (does not require discontinuation of the drug), allergic manifestations (skin rash, erythema, urticaria).
Application: a 6 g capsule is inserted into the vagina once, it can be reused for 3 consecutive days, a 10 g capsule is used for 2 days.
Advantages and disadvantages: plus - the remedy is effective, minus - it is not used during pregnancy.
Read more: How to cure thrush in one day?
Suppositories for 3 days of treatment
Livarol and ketoconazole
Livarol (price for 5 pieces - 660 rubles, for 10 pieces - 950 rubles).
Contraindications: 1st trimester of pregnancy, hypersensitivity to the components of the drug, in the 2nd and 3rd trimester of pregnancy, use with caution.
Side effects: itching and hyperemia of the vaginal mucosa, irritation, skin rash, urticaria.
Application: 1 suppository is injected into the vagina in the supine position, the course of treatment is 3-5 days, with chronic thrush - 10 days. Advantages and disadvantages: positive properties - a quick effect, no allergic reactions, a confirmed diagnosis is required to prescribe the drug, minus - with prolonged use, the pathogen becomes resistant to the active substance.
Pimafucin
Primafungin (250 rubles for 3 pieces), Pimafucin (250 rubles for 3 pieces, 550 rubles for 6 pieces)
Impact on the health of a pregnant woman and her fetus: the drug is approved for use.
Contraindications: hypersensitivity.
Side effects: slight irritation of the vaginal mucosa.
Application: 1 candle in the vagina, the course of treatment is 3-6 days.
Advantages: the drug is not dangerous to use during pregnancy.
Econazole
Gino-Pevaril (price 550 rubles for 3 pieces with a dosage of 0.15 mg, and 750 rubles for 15 pieces with a dosage of 0.05 mg), Elzhina (550 rubles for 9 pieces), Ifenek
Contraindications: hypersensitivity, 1 trimester of pregnancy (enters the systemic circulation), lactation, use with caution in the 2-3 trimester, Side effects: hyperemia of the mucous membrane, skin rash, itching.
Application: suppositories of 50 mg with a full course within 2 weeks, suppositories of 150 mg are used for 3 days, with a positive control analysis, repeat the course of treatment.
Benefits: an effective remedy for thrush
The best suppositories for thrush with course treatment
Irunin and itraconazole
The price of Irunin vaginal tablets is 500 rubles for 6 pieces, and 950 rubles for 14 pieces.
Contraindications: hypersensitivity, lactation, 1 trimester of pregnancy. Use with caution in the 2-3 trimester,
Side effects: itching, skin rash, burning (do not require discontinuation of the drug).
Application: tablets are placed in the vagina overnight for 7-14 days.
Advantages and disadvantages: plus - the drug is effective for relapses of candidiasis and resistance to other drugs against candidiasis, minus - is not used to treat pregnant women.
Macmiror complex
Macmiror complex (nystatin + nifuratel) price for 8 vaginal capsules - 1100 rubles.
Use during pregnancy: the drug is approved for use.
Contraindications: hypersensitivity to drug components.
Side effects: occasional skin rash, itching.
Application: insert 1 suppository into the vagina at night, the course of treatment is 8 days.
Advantages and disadvantages: plus - can be used during pregnancy, minus - high cost.
Miconazole
500-1000 r for 7 suppositories. Analogs: Ginezol 7, Mikozon, Dactarin, Gino-Dactanol
Combined funds: a combination of Miconazole with Metronidazole - Neo-Penotran (580-680 rubles for 14 pcs.), Klion-D 100 (price 170-220 rubles), Metormikon-Neo (300-350 rubles for 14 pcs.)
Contraindications: hypersensitivity to the components of the drug, lactation, 2-3 trimester of pregnancy with caution, diabetes mellitus, herpes, liver failure.
Side effects: itching and burning in the vagina, discomfort, diarrhea, abdominal pain, nausea.
Application: 1 suppository at night in the vagina, the course of treatment is 6-7 days, alcohol is contraindicated during treatment.
Advantages and disadvantages: positive qualities - efficacy in relapse, a wide range of actions, minus - the risk of use during pregnancy.
Fluomisan
Fluomisan (active ingredient: dequalinium chloride) is used as an antiseptic in gynecology (vaginal sanitation before surgery and before childbirth, bacterial vaginosis, vaginitis caused by thrush). Cost - 610 rubles for 6 vaginal tablets.
Contraindications: ulcers of the cervix and vagina, the period before sexual activity, 1-2 trimester of pregnancy.
Side effects: allergies, irritation of the vaginal mucosa.
Application: the capsule is inserted into the vagina once a day at night, the course of treatment is 6 days, stops during menstruation, then resumes.
Cheap candles for thrush
Clotrimazole
Clotrimazole (from 30 rubles), Candizol, Candibene, Candide B6, Canesten.
Contraindications: hypersensitivity, 1 trimester of pregnancy, lactation.
Side effects: pain in the abdomen and during intercourse, burning and itching in the vagina, cystitis, frequent urination, vaginal discharge, headache.
Application: 1 suppository intravaginally at night, the course of treatment is 6 days.
Advantages and disadvantages: positive properties - low cost of the drug, minus - side effects often appear, resistance rapidly develops in fungal strains.
Nystatin
Nystatin (price from 185 rubles for 10 suppositories with a dosage of 500,000 U), polygynax (370 rubles for 6 suppositories), Terzhinan (640 rubles for 6 suppositories), the drugs have an increased risk of dysbiosis.
Contraindications: hypersensitivity, pregnancy in the 1-3 trimester.
Side effects: nausea and vomiting, diarrhea, chills, abdominal pain.
Application: suppositories are placed in the vagina in the morning and in the evening, the course of treatment is 10-14 days.
Advantages and disadvantages: positive properties - the fungus does not develop resistance to Nystatin, it is used for recurrent thrush, has a low cost, minus - many side effects, a long course of treatment, the need to apply 2 times a day.
Iodoxide
Price: Iodoxide (330 rubles for 10 pieces), Betadine (470 rubles for 7 pieces, 600 rubles for 14 pieces)
Contraindications: 1 trimester of pregnancy, thyrotoxicosis, thyroid adenoma, hypersensitivity, use with caution in the 2-3 trimester of pregnancy, with renal failure, with lactation.
Side effects: allergic reaction, local hyperemia.
Application: vaginitis in acute form - 2 times a day, 1 suppository (course - 1 week), chronic form - once a day, the course of treatment is 2 weeks, it depends on the phase of the menstrual cycle.
Advantages and disadvantages: plus - it is used in a complex with bacterial vaginosis, it is possible to use it during menstruation, minus - a large number of contraindications.
Pros and cons of using suppositories for thrush
Advantages of topical preparations for the treatment of vaginal candidiasis:
- The agent is injected directly into the focus of the spread of fungi, which accelerates the therapeutic effect of treatment with modern means (Zalain, Livarol).
- A number of drugs can be used once, which is very convenient for use;
- Topical agents have reduced absorption, which significantly reduces the incidence of side effects.
Disadvantages of topical preparations:
- There are restrictions on sexual intercourse during treatment;
- Suppositories contaminate underwear;
- The funds are ineffective in complex forms of candidiasis, additional intake of drugs for oral administration is required, a repeated course of treatment;
- Potent combined drugs have such side effects as vaginal dysbiosis (Terzhinan, Polygynax), additional therapy with suppositories containing lactobacilli (Lactobacterin, Vagiflor, Lactonorma, Ekofemin, Acilact) is required.
Candles from thrush during pregnancy
General and local immunity is often reduced in pregnant women. The consequence of this is thrush. It is difficult to choose a safe drug for candidiasis during pregnancy, as many antifungal agents do not have safety data.
Suppositories approved for use for pregnant women:
- Suppositories with the active ingredient Natamycin (Pimafucin, Primafungin).
- Combined preparation with active ingredients Nystatin and Nifuratel - Macmiror complex;
- Preparations for use exclusively in the 2-3 trimester of pregnancy - Nystatin, Clortrimazole, Pimafucin, Gino-Pevaril, Gynofort vaginal cream, the time-tested Borax agent in glycerin (sodium tetraborate in glycerin). Medicines are used with extreme caution if the risk to fetal health does not outweigh the risk to maternal health.
- When the attending physician prescribes the drug Terzhinan in the 2-3 trimester of pregnancy, it should be noted that it contains the hormonal agent Prednisolone, and can be used in cases where the mother's health is at greater risk than the child's health.
Vaginal creams as a complementary treatment
In addition to suppositories for thrush, dosage forms such as creams are used:
- Econazole: Ekodas cream (250 rubles), Elzhina cream - 550 rubles;
- Fenticonazole: Lomexin cream (670 r);
- Clotrimazole: Canison - 170 rubles, Clotrimazole cream - 300 rubles, triderm - 770 rubles;
- Isoconazole: Travogen cream - 770 r;
- Butoconazole: Clindacin B prolonged cream - 660 r.
After treatment with anti-fungal drugs, patients are prescribed funds to replenish the number of lactobacilli on the vaginal mucosa:
- Vaginal capsules with lactobacilli Lactozhinal, Acilact, course of treatment from 1 to 10 days;
- Suppositories with Vagilak bifidobacteria, used 2 times a day, the course of treatment is from 5 to 10 days;
- Bifikol for oral administration, the course of treatment is 10 days.
[Video] Gynecologist online - how to approach treatment correctly so that thrush never comes back to you:
The author of the article: Lapikova Valentina Vladimirovna | Gynecologist, reproductologist
Education: Diploma in Obstetrics and Gynecology received at the Russian State Medical University of the Federal Agency for Healthcare and Social Development (2010). In 2013 completed postgraduate studies at N. N. N. I. Pirogova.
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