Desrinitis With Adenoids - Indications, Pros And Cons

2024 Author: Josephine Shorter | [email protected]. Last modified: 2024-01-07 17:49

Desrinitis with adenoids

Adenoids are abnormal overgrown tissues of the nasopharyngeal tonsil. The disease is most often diagnosed in children aged 3 to 7 years, although adults can sometimes get sick. With adenoids, there is difficulty in normal nasal breathing, night snoring, voice changes, rhinitis. The disease is dangerous for its complications, including: hearing impairment, decreased overall immunity, malocclusion, developmental delay, frequent infections, etc. Therefore, adenoids must be treated promptly.

If you start therapy in the early stages of the development of the disease, then conservative methods can be dispensed with. When the adenoids are running, it will be impossible to avoid surgery. Desrinitis is a drug that is often prescribed for adenoids. It helps to relieve inflammation and eliminate the main symptoms of the disease.

Content:

• General characteristics of the medicinal product
• Effect of Desrinitis in adenoids
• How to use Dezrinitis to treat adenoids?
• Potential harm
• When the drug cannot be used
• Important information
• Pros and cons of Dezrinit

General characteristics of the medicinal product

Desrinitis is a nasal spray that comes in plastic bottles equipped with a dispenser. The main active ingredient is mometasone furoate monohydrate, a topical glucocorticosteroid. Also, the composition of the drug contains auxiliary components (polysorbate, citric acid monohydrate, etc.), but they do not have any effect on the course of the disease.

The liquid in the vial with the drug has a milky color, it is represented by a homogeneous suspension. Vials containing 60 and 140 doses are available for purchase.

Effect of Desrinitis in adenoids

The medicinal properties of the drug Dezrinit are determined by its main active ingredient - mometasone.

The use of a nasal spray for adenoids can achieve the following effects:

• The drug fully blocks the cascade of the inflammatory response, blocking the production of inflammatory mediators (substances that the body itself synthesizes in order to fight infection).
• Reducing tissue swelling, facilitating nasal breathing.
• Prevention of further destruction of lymphoid tissue.
• Reducing the size of adenoid vegetation, which often avoids surgical intervention. Desrinitis is prescribed even for third-degree adenoids.
• Cure secretory otitis media as complications of adenoids.
• Improving aeration of the paranasal sinuses, spontaneous sanitation of the nasal cavity, unloading of the fistulas, which were previously covered by the overgrown tissue of the adenoids.
• Elimination of allergy symptoms.

The drug is prescribed for children who have undergone adenotomy procedure, which avoids repeated operations.

After local administration of the drug, it is possible to create its maximum concentration in the nasopharyngeal cavity directly on the adenoids. Therefore, the effect occurs quickly and lasts a fairly long period of time.

How to use Dezrinitis to treat adenoids?

Before the first use of the drug, immediately after opening the bottle, it will take 10 “empty” presses on the dispenser. This must be done in order to establish a stereotyped dose surge. At one time, 100 mg of the drug (50 μg of mometasone) comes out of the dispenser. If the drug is used regularly, then re-calibration is not required. Provided that the bottle has been inactive for two weeks, it will be necessary to repeat ten presses before using it.

Shake the bottle vigorously before injecting the drug into the nasal cavity. Before irrigating the nasal cavity, rinse it with saline or other antiseptic. The cleaner the nasal passages, the more effective the treatment will be.

As for the dosage, its average values are equal to two injections into each nasal passage once per knocking. The doctor should select the dosage, since it can be changed, depending on the severity of the patient's condition. If necessary, the frequency of application of the drug is increased up to twice a day.

For the treatment of children, you can try to start treatment with a single injection into each nostril, which is repeated once a day. If there is no effect, then two injections are performed in each nostril. When it is possible to achieve control of the clinical picture, the dosage is reduced again.

You can expect the effect of using the drug Dezrinit after 12 hours from the first use.

Important rules for the use of a vial of a drug that avoid the development of atrophy of the nasal mucosa:

• The bottle is inserted into the nostril strictly vertically.
• Spray the drug into the right nostril with the left hand, and into the left nostril with the right hand.
• It is impossible to exceed the recommended number of injections.

The drug can be used for a long time. Sometimes it is prescribed for a period from 9 months to a year. This does not affect the effectiveness of the drug, and tissue atrophy is not observed in the nasal passages. For the treatment of adenoids, it is advisable to use the drug in courses of 1-3 months, followed by a break of 1-2 months. Then the course of treatment can be repeated.

Potential harm

The use of Desrinit is associated with a number of side effects, although in most cases the drug is well tolerated by patients.

The most common negative health manifestations are: headaches, nosebleeds, a burning sensation in the nasal cavity, the formation of ulcers on the mucous membrane of the nasal passages.

Allergic reactions such as bronchospasm, shortness of breath, angioedema or anaphylactic shock are extremely rare. Rare side effects also include perforation of the nasal septum, irritation of the pharyngeal wall, distorted sense of smell and taste, increased intracranial pressure, cataracts, or glaucoma.

When the drug cannot be used

It is not recommended to prescribe the drug to mothers who are breastfeeding, as well as to pregnant women. Do not use Dezrinit to treat children under two years of age.

Other contraindications for use:

• The presence of individual hypersensitivity to the components that make up Dezrinit.
• Recently postponed surgery on the nose.
• "Fresh" nose injury. The drug is not prescribed until the wound is completely healed.

The following conditions are not a contraindication, but the following conditions are required when prescribing the drug: any respiratory tract infection, eye damage, prolonged and sluggish inflammation of the nasal mucosa caused by bacterial, fungal or mixed pathogenic flora.

Important information

The systemic availability of the drug is less than 0.1%. This means that it practically does not enter the bloodstream and does not spread throughout the body. On this occasion, clinical studies were carried out, which made it possible to establish that in children who took therapy with Dezrinitis for a year, there were no violations in growth and development, the synthesis of corticosteroids by the adrenal glands did not change. In the blood, the drug is not determined by any available methods.

The mucous membrane of the nasal passages during the use of the drug does not undergo atrophic changes, despite long-term treatment with the drug Dezrinit. However, the use of corticosteroid drugs always carries the risk of tissue atrophy, so periodic examination by an otolaryngologist is a must.

If a patient develops a fungal infection while undergoing treatment, then he needs to abandon Dezrinitis.

Against the background of treatment with Dezrinitis, suppression of local immunity is observed. This requires special care on the part of the patient. He needs to minimize contact with infected people, as the chances of infection are significantly increased.

Both children and adults who receive nasal glucocorticosteroid therapy should be under medical supervision.

The drug can be used to treat adenoids in people with bronchial asthma. Moreover, improving nasal breathing in such patients helps to stabilize their condition.

Desrinitis is not able to fight against pathogenic flora. Therefore, if the disease is provoked not only by allergens, but also by viruses, bacteria or fungi, then treatment with specific drugs will be required.

An overdose of the drug is unlikely, since its bioavailability is extremely low. Nevertheless, if a dose has been administered that significantly exceeds the permissible one, it is necessary to consult a doctor and spend some time under the supervision of specialists. No specific measures should be taken.

It is not recommended to simultaneously combine the drug Dezrinit with other drugs from the group of glucocorticosteroids. This can lead to the suppression of adrenal function.

It should be borne in mind that the drug cannot be stored for more than 2 months if it has been opened. When the integrity of the package is not violated, the shelf life of the medicinal product is 2 years.

Pros and cons of Dezrinit

Advantages of the drug Dezrinit:

• The drug allows not only to eliminate the symptoms of adenoiditis, but also to treat the disease.
• In some cases, the drug makes it possible to avoid surgery aimed at removing the overgrown tissue of the adenoids.
• The drug, unlike most other glucocorticosteroids, does not lead to atrophy of the mucous membrane of the nasal passages and sinuses.
• The drug can be used for a long time.
• The healing effect comes quickly.

Cons of the drug Dezrinit:

• The drug is available by prescription.
• It can cause side effects.
• The drug has contraindications.
• The drug suppresses local immunity, which increases the risk of contracting infectious diseases.
• The drug has an age limit. It is not prescribed for children under two years of age, although adenoids are not often diagnosed at this age.
• The drug has no antiviral, antifungal or antibacterial activity.

Article author: Mochalov Pavel Alexandrovich | d. m. n. therapist

Education: Moscow Medical Institute. IM Sechenov, specialty - "General Medicine" in 1991, in 1993 "Occupational Diseases", in 1996 "Therapy".