2024 Author: Josephine Shorter | [email protected]. Last modified: 2023-12-16 21:43
Piracetam or Thiocetam - which medicine to choose?
2019-18-12
Piracetam is a drug that affects the brain. This nootropic facilitates the transmission of nerve impulses in the brain. Piracetam is part of the Thiocetam preparation.
Thiocetam contains thiotriazoline in addition to piracetam. This ingredient prevents reactive oxygen and free radicals from damaging the brain.
Thiocetam is able to positively influence memory and attention. In addition, it acts on the vascular wall, platelets and red blood cells, increasing the blood supply to the brain and the nutrition of nerve cells. It is also often used to treat chronic headaches. The medicine can be used in patients with chronic cerebrovascular accident (including those who have suffered a stroke), as well as in those suffering from diabetes mellitus complicated by encephalopathy.
Content:
- An important difference between Thiocetam and Piracetam
- Indications for the use of Thiocetam
- Thiocetam release form and dose
- Side effects
- Contraindications for use
- Application during pregnancy and lactation
- Application for impaired renal function
- Application in children
- Use in elderly patients
- special instructions
- Overdose
- Thiocetam drug interactions
- Pyrocetam drug interactions
- Terms of dispensing from pharmacies
An important difference between Thiocetam and Piracetam
Thiotriazoline and piracetam enhance the positive therapeutic effect and reduce each other's side reactions.
Unlike Piracetam, Thiocetam does not stimulate mental processes. This is due to the low dose of piracetam in Thiocetam. Thiotriazoline allows reducing the dose of this component, eliminating undesirable reactions: it enhances the effect of piracetam. Therefore, piracetam with thiotriazoline in minimal dosages as part of one drug has a stronger therapeutic effect than piracetam alone.
Indications for the use of Thiocetam
Thiocetam is indicated for conditions such as:
- chronic cerebral ischemia, for example, in old age. Lack of blood circulation in this case is associated with vasoconstriction due to atherosclerotic plaques, which leads to frequent headaches;
- the consequences of a stroke (during the recovery period);
- diabetes mellitus complicated by encephalopathy;
- chronic headaches associated with poor circulation in the brain.
Thiocetam release form and dose
Both piracetam and thiocetam come in two forms: tablets and ampoules with a solution for intravenous or intramuscular administration.
The composition of 1 ml of the drug Thiocetam contains 100 mg of piracetam and 25 mg of thiotriazoline. An injection drug is administered in case of impossibility of oral administration or with severe pathology. The course of injections is prescribed for 2 weeks. After it, you need to take Tiocetam tablets.
One Thiocetam tablet contains 200 mg of piracetam and 50 mg of Thiotriazoline. The medicine is taken 30 minutes before meals. It is advisable to take the last time the drug is not later than 5 pm.
The dose of medication is selected depending on the cause of the impaired blood circulation in the brain.
Side effects
When taking these drugs, the following side effects may occur:
- insomnia, exacerbation of epilepsy, impaired consciousness, nervous irritability, dizziness, imbalance, hallucinations, tinnitus, anxiety;
- heart palpitations, rhythm disturbances, hypertension, heart pain;
- abdominal pain, vomiting, diarrhea;
- anaphylactic shock, rash, itching, fever, angioedema;
- weight gain;
- shortness of breath, choking;
- soreness at the injection site.
It is important that Thiocetam is devoid of such side effects as a pronounced stimulating effect on the nervous system, which is typical for Piracetam.
Contraindications for use
These medicines are contraindicated in the following conditions:
- hemorrhagic stroke;
- hypersensitivity to components;
- mental or motor agitation;
- pregnancy and the period of breastfeeding;
- severe renal impairment;
- age up to 18 years;
- Chorea of Huntington.
Application during pregnancy and lactation
These medicines are not recommended for use during gestation and lactation.
Application for impaired renal function
In severe kidney failure (creatinine elimination rate less than 20 ml / min), the drug is contraindicated. When excreting creatinine from 20 to 80 ml / min, Piracetam and Thiocetam should be used with caution.
Application in children
Thiocetam and Piracetam are not recommended for children.
Use in elderly patients
The elderly require caution when prescribing drugs. These patients are more likely to have adverse reactions. With prolonged use of the drug, it is necessary to monitor renal function and adjust the dose depending on the degree of creatinine excretion.
special instructions
During the period of therapy, it is recommended to refrain from work requiring increased attention. This includes driving a car.
Overdose
In case of an overdose, the appearance or intensification of the side effects of the drugs is possible. Treatment requires discontinuation of drugs and post-symptomatic therapy.
Thiocetam drug interactions
It should be taken into account that the drug cannot be prescribed if the patient is taking thyroid hormones due to possible side effects: insomnia, impaired consciousness and mental agitation. Thiocetam enhances the effects of pain relievers and antidepressants. It is forbidden to take Thiocetam with products that have an acidic pH.
Pyrocetam drug interactions
Piracetam is almost completely excreted by the kidneys. Drug interactions of this drug are most likely when combined with antiplatelet agents, neuroleptics, antiepileptic and psychotropic drugs.
Terms of dispensing from pharmacies
Thiocetam and Pyrocetam are both prescription drugs.
Thiocetam is a combined drug that improves cerebral circulation in various conditions. It eliminates frequent headaches, improves memory, attention, fights asthenia. The drug is devoid of side effects of piracetam, and the combination with thiotriazoline allows you to achieve maximum effect even with minimal doses of the drug's constituents.
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