Maninil - Instructions For Use, Reviews

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Maninil - Instructions For Use, Reviews
Maninil - Instructions For Use, Reviews
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Maninil - instructions for use

Maninil
Maninil

Maninil is a drug for the treatment of type 2 diabetes. The main active ingredient in it is glibenclamide. Maninil is often prescribed for people with diabetes.

At the same time, patients have many questions, which we will answer in this article. For instance:

  • Which dose is more effective - 1.75, 3.5 or 5 mg per day.
  • Which drugs are more effective than Maninil.
  • What to do if treatment doesn't work.
  • Which drug is better: Maninil, Glucophage, Diabeton or Metformin and more.

Content:

  • Instructions for use
  • Reception scheme
  • What is better Maninil or Diabeton?
  • What is better Maninil or Glucophage?
  • Can Maninil and Metformin be taken together?
  • How to replace Maninil if it doesn't work?
  • Which pills are stronger than Maninil?
  • Reviews

Instructions for use

the effect

The drug stimulates the production of insulin by the beta cells of the pancreas, promotes its better absorption in the cells of the body, and reduces the flow of glucose into the blood from the liver. In parallel, the frequency of platelet adhesion decreases, which prevents the formation of blood clots. The drug is rapidly absorbed from the gastrointestinal tract, so it can be taken before meals. Half of the drug is excreted by the kidneys, and the other half by the liver. Maninil does not accumulate in the body.

When to take The indication for treatment is type 2 diabetes, which cannot be corrected through diet and physical activity.
Contraindications
  • Type 2 diabetes mellitus in the stage of decompensation with ketoacidosis or coma.
  • Severe liver and kidney pathologies.
  • Alcoholism.
  • Acute diseases of an infectious nature.
  • The recovery period after surgery, severe burns and other injuries.
  • Low-calorie diet, problems in the digestive system.
  • Intolerance to glibenclamide and sulfonylurea derivatives.
  • special instructions If a person develops negative health reactions, then Maninil should be abandoned. During treatment, it is recommended to refrain from work and other activities associated with increased concentration of attention.
    Dosage

    Maninil is taken in the morning and evening before meals. The drug is drunk whole, not chewed. The dosage is selected by the doctor. Drug release form: tablets of 1.75, 3.5 and 5 mg. Treatment should be started with taking half a tablet. The average dose is one tablet 2 times a day. Sometimes, but extremely rarely, patients are prescribed 2 tablets 2 times a day.

    Side effects Adverse events develop most often with incorrect selection of the dose. So, taking Maninil can lower blood sugar levels and lead to the development of hypoglycemia. This is a dangerous condition that can be fatal. Other side effects include nausea, vomiting, fever, arthralgia, visual impairment, and hypersensitivity to sunlight.
    Period of gestation and lactation period Taking the medicine is not allowed. At this time, only insulin injections can be used.
    Interaction with other drugs Before taking Maninil with other drugs, you need to consult a specialist. Maninil can react with steroids, ACE inhibitors, beta-blockers, coumarins, pentoxifylline, phenibutazole, reserpine, etc.
    Overdose

    When taking an excessive dose of the drug, there is an increase in sweating, tremors of the limbs, overexcitation, headaches, and increased appetite. The person may start to feel sleepy. If the overdose is significant, then a lethal outcome is possible. Therefore, this condition requires urgent medical attention.

    Release form, storage features and composition Release form: tablets of 1.75, 3.5 and 5 mg. The color of the tablets ranges from pale pink to pink. Main active ingredient: glibenclamide. Excipients: lactose monohydrate, starch, silicon dioxide, methylhydroxyethylcellulose, magnesium stearate, red cochineal. The drug does not require special storage conditions. The shelf life is 3 years.

    Maninil is produced by the German company Berlin-Chemie AG / Menarini Group. Its price is quite affordable for most people. An analogue of the drug is the drug Glimstrada, which is also produced in Germany.

    Inexpensive analogues are produced by the Atoll company, which is registered in Russia. Although Maninil is also not an expensive drug. Therefore, it is inappropriate to replace it with analogs.

    Reception scheme

    During administration, the tablet must be swallowed whole, or broken into 2 parts, but not chewed. It is drunk twice a day - in the morning and in the evening. The dose is selected by the endocrinologist. Self-administration of Maninil is unacceptable, since an incorrect dosage can provoke the development of side effects. After taking the drug, you need to eat so that the blood sugar level does not drop to critical levels.

    If Maninil in the dosage prescribed by the doctor has ceased to have the desired effect, then it cannot be increased. You need to see a doctor. You will most likely need to switch to insulin injections.

    What is better Maninil or Diabeton?

    Maninil and Diabeton are based on different active ingredients, but they belong to the same group (sulfonylurea derivatives). They lower blood sugar levels, but if the dose is incorrectly selected, hypoglycemia may develop.

    Diabeton lasts longer than Maninil. Therefore, it is sufficient to take it once a day.

    What is better Maninil or Glucophage?

    Glucophage, unlike Maninil, not only helps to lower blood sugar levels, but also avoids the development of severe complications of diabetes. However, preference should be given to the original drug, and not to its analogues. You can also pay attention to the drug Glucophage Long.

    Can Maninil and Metformin be taken together?

    It is not recommended to combine the reception of Maninil and Metformin. On the basis of metformin, drugs are produced called Glucophage and Siofor.

    How to replace Maninil if it doesn't work?

    If the pancreas has stopped producing insulin, taking Maninil will not have the desired effect. This means that the disease is progressing. If the patient does not consult a doctor and does not urgently start receiving insulin injections, he will die from the severe consequences of diabetes.

    Which pills are stronger than Maninil?

    Maninil is a potent drug used to lower blood sugar levels. If it stops working, then the patient needs insulin injections. No other drugs will help.

    Reviews

    Patients indicate that Maninil is an affordable drug. Therefore, the choice often falls on him.

    You can find reviews stating that after a few years from the start of taking Maninil it stops working. However, there are also positive reviews about this drug.

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    Author of the article: Alekseeva Maria Yurievna | Therapist

    Education: From 2010 to 2016 Practitioner of the therapeutic hospital of the central medical-sanitary unit No. 21, city of elektrostal. Since 2016 she has been working in the diagnostic center No. 3.

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