Urinary incontinence pills and medications
Urinary incontinence is a serious problem faced by both men and women. It affects not only children, but also adults. Especially often, urinary incontinence is observed in women, which is explained by the physiological characteristics of their body, as well as complications during labor. Self-medication does not bring the desired results, since the treatment of urinary incontinence requires an integrated approach. It is very problematic to do without medical help. Only a doctor can find out the exact causes of urinary incontinence and prescribe medications that will help to cope with the problem.
Medicines for urinary incontinence are selected based on the etiology of the disease. Therefore, a specialist consultation is mandatory. In medical practice, stress and urgency urinary incontinence is most common. In the first case, urine flows out of the bladder due to the weakness of the pelvic muscles and the sphincter, and in the second case, the cause of its incontinence is organ hyperactivity. Each condition requires correction with various drugs.
Content:
- Table of Essential Medicines for Urinary Incontinence
- Ovestin suppositories for urinary incontinence
- Minirin
- Driptan
- Picamilon
- Duloxetine
- Melipramine
- Pantocalcin
- Pantogam
- Remedies for urgent form
Table of Essential Medicines for Urinary Incontinence
Preparations for the normalization of the nervous system:Drugs that relax the bladder wall (anticholinergic drugs):
Analogues of synthetic antidiuretic hormone:
| Medicine | Mechanism | Method of reception | the effect |
|
Pantogam 
|
Promotes the development of a "sentry" reflex |
Adults: 1-2 tablets 30 minutes after a meal. For children 1 / 2-1 tablet after meals. The drug is taken 3 times a day. Reception course: 3 months. |
Contributes to the normalization of the brain. |
|
Glycine 
|
Has a sedative effect, eliminates depression, normalizes sleep. | The tablet is placed under the tongue and dissolves until completely dissolved. You can take the drug 1-2 times a day. The course of treatment is 14-30 days. |
|
|
Phenibut 
|
Improves metabolic processes in the cerebral cortex, normalizes sleep. | The course of treatment is from a week to 10 days. Take 1 tablet a day. If the drug is prescribed to children, then the dose is calculated individually. | The drug helps to reduce anxiety, which can improve the quality of sleep. |
|
Melipramine 
|
Allows you to make sleep less sensitive, increases the volume of the bladder, improves the sphincter function. | 1 tablet 3 times a day, with or without food. The minimum course of treatment is 14 days. | The walls of the bladder will be relaxed, which in turn prevents the flow of urine. The dream will be full, but sensitive. |
|
Rakedorm 
|
The drug eliminates muscle spasm, helps to normalize night rest |
1 tablet 30 minutes before bedtime. Children are prescribed 1/2 tablet. |
|
|
Driptan 
|
Relieves hypersensitivity from the bladder, relaxes its walls, helps to reduce the number of organ contractions. |
1 tablet, 2-3 times a day (the last dose of the drug should be before bedtime). Children are prescribed 1/2 tablet 2 times a day. |
Taking the drug allows you to prevent nighttime urination by relaxing the wall of the bladder. |
|
Spazmex 
|
The tone of the sphincter increases, the tone of the bladder is weakened. | 1 tablet, 2-3 times daily before meals. The course of treatment is 3 months. | |
|
Desmopressin 
|
Helps reduce the amount of urine produced during a night's rest. | The course of treatment is 2-3 months. The dose of the drug is adjusted individually, but it should not exceed 10 tablets per day. | The bladder does not fill with urine at night. |
|
Minirin 
|
It affects the functioning of the kidneys, prevents them from producing large amounts of urine. | The drug is taken before bedtime, once. The course of treatment is no more than 3 months. | During the night's rest, the bladder does not fill with urine. |
Ovestin suppositories for urinary incontinence
Pharmacological properties. Ovestin suppositories contain the hormone estriol, therefore they are prescribed for the treatment of atrophy of the muscles of the genitourinary tract, which is observed against the background of hormonal imbalance (lack of estrogen). The pharmacological effect of the drug is achieved due to the female hormone estriol, which restores the normal epithelium of the urethra and vagina, preventing the development of atrophic changes in the tissues. Most often, such violations occur in a woman during and after menopause.
Method of administration. Suppositories are administered intravaginally, before a night's rest, in the supine position. For urinary incontinence, 1 suppository is prescribed per day for the first few weeks. The duration of use of the drug is determined by the doctor on an individual basis. Then the dose is reduced and 1 suppository is administered 2 times a week.
Side effects:
- Itching and irritation in the vaginal area.
- Pain, hypersensitivity reactions - all these symptoms are observed with the use of impressive doses of the drug.
- Neoplasia (malignant and benign).
- Lung embolism.
- Stroke and heart attack.
- Purpura of hemorrhagic type.
- Cholelithiasis.
- Chloasma.
- Alopecia.
- Erythema (nodular and multiforme).
Suppositories are not prescribed for women who are suspected of having breast cancer, and they should not be used if the patient has a history of breast cancer. It is worth paying attention to such contraindications to the use of the drug as: diabetes mellitus, heart attack, angina pectoris, venous thrombosis, endometrial hyperplasia, exacerbation of kidney disease.
Reviews. Most women who have used Ovestin suppositories for urinary incontinence note their high effectiveness. The most common side effects they call the occurrence of a burning sensation in the vaginal area.
So, Ovestin suppositories can be used in the complex treatment of urinary incontinence, which is caused by a lack of estrogen in the body. However, the drug has many contraindications and side effects, so it can be used only after medical advice.
Minirin
Mechanism of action. The drug Minirin has proven itself well in the fight against enuresis in children. The composition of the drug contains a synthetic analogue of the hormone, which is produced by the back of the pituitary gland. The effect occurs already 15 minutes after taking the drug and lasts for 10 hours.
Minirin cannot be administered alone. It is used only on the recommendation of a doctor. There is no single dosage of the drug, the doctor selects the dose on an individual basis.
Contraindications:
- Polydipsia (congenital and psychogenic).
- Heart pathology.
- Obesity.
Features of treatment with Minirin:
- If there is no effect of treatment, then the dose should be increased.
- The average course of treatment is 3 months.
- The course, if necessary, can be repeated, taking a break of 7 days.
- Do not take the tablets with water, do not drink the liquid after taking the medicine.
Reviews. Reviews on the use of the drug are most often positive. Parents call one of the advantages of the drug that the children do not refuse to take the drug (it must be dissolved under the tongue), since the tablet has no taste. In addition, Minirin allows you to get rid of urinary incontinence, even in cases where other drugs were ineffective.
Separately, it is worth noting the high cost of the drug, but it is justified by the fact that the drug really works and eliminates the unwanted symptom. The effect is observed already several days after the start of treatment. Parents point out that relapses in children do not occur after a course of treatment.
As for side effects, they are extremely rare. Among the undesirable phenomena are: headaches, abdominal pain, nausea. As a rule, Minirin is well tolerated.
Driptan
Driptan is a drug that comes in pill form. The therapeutic effect is achieved due to the main active ingredient called oxybutynin hydrochloride.
Mechanism of action. The drug relaxes the detrusor of the bladder, thereby increasing its capacity. In parallel, the frequency of contraction of the walls of the organ decreases, the spasm is relieved, due to which a person does not have the urge to urinate with an incomplete bladder. The effect can be felt already 45 minutes after taking the drug.
Driptan is prescribed for the treatment of imperative urinary incontinence in adults with an overactive bladder, for the treatment of incontinence in cystitis, after undergoing bladder surgery. Driptan can be used to treat enuresis in children against a background of unstable bladder function, with nocturnal enuresis, and with idiopathic organ dysfunction.
Contraindications to the use of the drug:
- Age up to 5 years.
- Increased body temperature.
- Ulcerative colitis.
- Obstruction of the urinary tract.
- Pregnancy and lactation.
- Myasthenia Gravis.
- Gastroesophageal reflux.
- Colon diseases, colostomy, ielostomy, intestinal obstruction.
Since the drug has contraindications for use, it cannot be prescribed independently. The drug is taken only on the recommendation of a doctor, who individually determines the dose for a particular patient. Average dosage: 1 tablet, 2-3 times a day for adults and 1/2 tablet 2 times a day for children.
Side effects. Possible disorders of the digestive system (vomiting, dry mouth, nausea), abdominal pain, disturbances in the central nervous system (drowsiness, headache, etc.), visual disturbances, dysuria, urinary retention, tachycardia, arrhythmia, allergic reactions …
Reviews. If we consider the reviews, Driptan is quite well tolerated by both adults and children. However, it must be applied correctly, without exceeding the dosage.
Patients treated with Driptan indicate its effectiveness in urinary incontinence. Some people have noticed abdominal pain that disappears after the drug is discontinued.
Picamilon
The mechanism of action. Picamilon is prescribed for the treatment of urinary incontinence in children and adults. It has a positive effect on the functioning of the bladder, as it reduces detrusor hypoxia. Therefore, it is often prescribed in complex therapy for a neurogenic bladder, for violations of the urodynamics of the urinary tract in a hyperreflex type. Taking Picamilon improves the storage function of the bladder.
In addition, the effect of the drug is based on its ability to dilate the vessels of the brain, to provide antioxidant, tranquilizing and psychostimulating effects. Due to the normalization of the functioning of the nervous system, it becomes easier for a person to restrain urges. Sleep will be of better quality, but more sensitive, thus avoiding nighttime urine leaks.
Contraindications and side effects. It is forbidden to treat children under the age of 3 years with Picamilon, it is not prescribed for lactating and pregnant women, as well as against the background of kidney disease.
Side effects are very rare in both children and adults. Among them are noted allergic reactions, nausea, headaches, overexcitation, increased irritability.
Reviews. Most of the reviews about this drug are positive. However, its effect on urinary incontinence is not always sufficient.
Duloxetine
The mechanism of action. Duloxetine belongs to antidepressant drugs. It is recommended to use it for frequent urge to urinate, as it has a sedative effect and has a positive effect on the nervous regulation of the bladder. Also, the drug helps to relax the muscles of the organ, but to reduce the muscle of its sphincter.
Duloxetine is recommended for stress urinary incontinence.
Side effects and contraindications:
- Insomnia and drowsiness.
- Dizziness.
- Vision problems.
- Shaking hands.
- Decreased appetite.
- Increased fatigue.
- Dry mouth.
- Constipation or diarrhea.
It is important to pay attention to contraindications to the use of this drug, including: glaucoma, breastfeeding, pregnancy, age under 18 years, renal and hepatic failure, high blood pressure.
It should be taken into account that abrupt withdrawal of the drug threatens the occurrence of headaches, surges in blood pressure, tachycardia and dizziness attacks.
Melipramine
Mechanism of action. Melipramine is an antidepressant drug that is also used as an antidiuretic. Its mechanism of action is based on a decrease in the depth of sleep, which makes it more sensitive and enables a person to wake up when the bladder is full. The drug is available in injections for intramuscular administration, in capsules and tablets. For the treatment of enuresis, it is most often the tablet form of the drug that is prescribed.
Treatment of urinary incontinence with Melipramine can be started in children from 6 years of age. The duration of taking the drug is strictly limited by medical recommendations. Melipramine is not prescribed for children under 6 years of age.
How the drug is taken. The dosage is chosen by the doctor. It is recommended to start therapy with minimal doses, increasing it if the desired effect is absent. Average dose: 1 tablet once a day, 30 minutes before bedtime. To calculate the dose more correctly, you need to know the patient's weight. The calculation is based on the scheme: 1 mg of active ingredient per 1 kg of weight. The average duration of treatment is 2 months.
Side effects and contraindications. Melipramine is not prescribed for people with diabetes, liver and kidney diseases, against the background of exacerbation of infectious diseases, with tuberculosis and heart pathologies.
As for side effects, such undesirable manifestations as:
- Drop in blood pressure.
- Headaches.
- Sleep disturbance.
- Delayed urination.
- Dry mouth.
- Allergic reactions.
- Nausea and vomiting.
- Obesity.
Reviews. Most people who have taken Melipramine for urinary incontinence are pleased with its effect. It will be noticeable after a few days from the start of therapy. However, it is important that the drug is prescribed by a doctor, as its independent use can only aggravate the existing problem. The price for Melipramine is very affordable, which is its undoubted advantage.
Pantocalcin
Mechanism of action. Pantocalcin is a nootropic drug that has a wide spectrum of action. It is an antagonist of GABAb receptors, helps to eliminate autonomic disorders, increases the volume of the bladder, reduces the amount of urination, and eliminates urgency.
Dosage for urinary incontinence. Depending on the age of the patient, 25-50 mg of the drug is prescribed, 3 times a day. You need to take it in the morning and evening. The course of treatment is 60 days.
Side effects and contraindications. The drug gives side effects extremely rarely. At the same time, positive dynamics is observed in most people suffering from urinary incontinence.
As for contraindications, Pantocalcin is not recommended to be prescribed to children under the age of 3 years, since it is produced exclusively in the form of tablets. Other contraindications are severe violations in the liver and kidneys.
Reviews. Reviews on the treatment with Pantocalcin are mostly only positive. A properly selected therapeutic course allows you to achieve stable remission, or complete elimination of urinary incontinence. If we consider the negative consequences of taking the drug, then among them one can distinguish increased irritability and excessive distraction. Although it has not been established that these effects were triggered by the administration of Pantocalcin.
Pantogam
The mechanism of action on the body. Pantogam is a nootropic drug that is prescribed for the treatment of urgent urinary incontinence. The drug has a moderate sedative effect, stimulates the metabolism in neurons. The positive therapeutic effect of Pantogam in the treatment of secondary enuresis is explained by its vegetotropic activity, as well as its ability to influence the functions of the urinary bladder sphincter. The studies carried out have made it possible to establish that Pantogam can effectively correct neurotic conditions that often accompany enuresis in childhood.
Application features:
- The dose of the drug is gradually increased over a period of 10-20 days.
- Then the dose is gradually reduced over 10-20 days until complete cancellation.
The course can be repeated 2-3 times a year.
The drug is prescribed for the treatment of urinary incontinence in children, adults and the elderly. The average adult dose is 3 tablets per day. The drug is taken after meals. For children, there is such a dosage form as syrup, which is very convenient.
Contraindications and side effects. The drug is not prescribed during the first trimester of pregnancy, as well as people suffering from severe kidney disease. As for side effects, they are extremely rare and are reduced to allergic skin rashes, rhinitis and conjunctivitis.
Remedies for urgent form
To eliminate the hyperactivity of the bladder, anticholinergics are prescribed, among which: Novitropan, Driptan, Roliten, Uroflex, Urotol, Detrusitol. They act on the detrusor of the bladder. However, side effects after taking these drugs include such conditions of the body as: constipation, drowsiness and dizziness.
A new generation of drugs has a relaxing effect on the detrusor, such as:
- Vesicar (Solifenacin).
- Spazmex (trospium chloride).
- Toviaz (Fesoterodin).
- Mirobegron (Begming). This drug has a minimal set of side effects and can significantly increase the reserves of the bladder.
Self-medication of an urgent form of urinary incontinence with any medication is unacceptable. During the course of the therapeutic course, you should stop drinking alcohol.
Author of the article: Lebedev Andrey Sergeevich | Urologist
Education: Diploma in the specialty "Andrology" received after completing residency at the Department of Endoscopic Urology of the Russian Medical Academy of Postgraduate Education in the urological center of the Central Clinical Hospital No. 1 of JSC Russian Railways (2007). Postgraduate studies were completed here by 2010.
