Treatment Of Chlamydia In Women And Men - Treatment Regimen

2024 Author: Josephine Shorter | [email protected]. Last modified: 2024-01-17 02:10

Chlamydia treatment regimen in women and men

Chlamydia is a sexually transmitted disease that in most cases manifests itself unpredictably. The complexity of its treatment lies in the fact that even after undergoing a course of antimicrobial therapy, the patient is not insured against the exit of the infection from the latent period and the resumption of the clinical picture of the disease. The reason is the presence of chronic urogenital chlamydia in most of the patients. For the treatment of such a development of chlamydia, the traditional therapeutic regimen may be ineffective.

According to experts, this is due to the fact that the patient's body gives a pathological reaction and an inadequate immune response to the presence of chlamydia that has affected the genitourinary system. This is evidenced by data from medical studies aimed at studying how effective the correction of impaired immunity is in chlamydia. The results obtained indicate that the chronic form of the disease in 70% of cases can be overcome without antibiotic therapy. Spontaneous cure in this case occurs exclusively due to immunocorrection.

The only obstacle to the use of this method is the insensitivity of the lymphocytes of a patient with chlamydia to immunomodulators. To determine the body's resistance to drugs that form the immune response, it is necessary to conduct a complete study of the patient's immunity.

Content:

• The choice of drugs in the treatment of chlamydia
• Antibiotics for chlamydia
• Chlamydia treatment regimen

The choice of drugs in the treatment of chlamydia

This infection provokes an active inflammatory process. To stop it, the complex use of drugs from various pharmacological groups is necessary. Drugs and treatment regimens for chlamydia are selected individually, since it is necessary to take into account the characteristics of the patient's body, the duration and intensity of the inflammatory process, the results of laboratory tests - liver tests, general blood tests and urine cultures, immunograms, blood tests by PCR, ELISA.

Preparations for stimulating the immune response are an indispensable part of the complex treatment of chronic chlamydia and other sexually transmitted diseases. The lack of an adequate immune response to the infection means the almost complete uselessness of antibiotic therapy and the impossibility of a complete cure.

Information about drugs is provided for informational purposes only. Prescribing treatment is the prerogative of a dermatovenerologist, who necessarily takes into account the data of laboratory tests, anamnesis, as well as what concomitant pathologies the patient has.

Interferon preparations

Chlamydia treatment regimen
Cycloferon	Intramuscularly 200 mg 10 days, every day
Amiksin	Only in the period of relapse 1 r / day 250 mg. 2 days, then 125 mg. every other day within a month
Ridostin	Only in the period of relapse 8 mg. intramuscularly No. 3, after 3 days
Neovir	Only during the relapse period 250 mg intramuscularly every day No. 3, then every other day No. 3
Reaferon	Every day 1 million intramuscularly for 14 days
Poludan	Every day 200 mcg intramuscularly No. 10
Leukinferon	Intramuscularly 2-3 times a week for 21 days
Interlock	Every day intramuscularly for 14 days 500,000 IU

Immunomodulators

Chlamydia treatment regimen
Polyoxidonium	6 mg every other day, intramuscularly No. 10
Timalin	Intramuscularly every day No. 10
Derinat	5 ml intramuscularly 1 time in 3 days No. 5-10

Systemic enzyme therapy

Highly active mixtures of plant and animal origin, containing natural enzymes, are successfully used in the treatment of chronic chlamydia. Enzyme therapy has a positive effect on the body's immune response and repair processes. Systemic enzyme therapy allows to concentrate antibiotics in the foci of infection development, to reduce the intoxication of organs and tissues, to stimulate the liver and kidneys, and to help the patient recover faster.

Chlamydia treatment regimen
Wobenzym	3 table. 3 r / day for a month 30 minutes before meals
Phlogenzyme	2 table. 3 r / day for a month 30 minutes before meals
Longidaza	Intramuscularly 2-3 times a week for a month or suppositories 1 time a day at night No. 10-20
Trypsin	Intramuscularly No. 10

The use of vitamin complexes, drugs from the group of antioxidants strengthens the immunity of a patient with chlamydia, provides an adequate response to an infectious invasion of the body, therefore, in treatment regimens for chlamydia, agents from this pharmacological group play an important role.

Antioxidants and Synergists:

Chlamydia treatment regimen
Thiosulfate Na	10.0 ml IV daily, for a course of 10 injections (in acute process)
Vitamin E	1 capsule 2 r / day 14 days
Vitamin C	3 tab. 3 r / day 14 days
Glutamic acid	2 tab. 3 r / day 14 days

Hepatoprotectors

Hepatoprotectors are used to protect the liver from the negative effects of toxins and maintain its functioning to neutralize the pathological side effects of antibiotics. In addition to their protective function, these drugs have antioxidant, immunomodulatory, and anti-inflammatory properties. Since antibiotics are widely used in the treatment of chlamydia, which have side effects in the form of toxic effects on the body, drugs from the group of hepatoprotectors are vital for the restoration of the liver and the whole body.

Chlamydia treatment regimen
Carsil	1 tab. 3 r / day for a month
Essentiale Forte	2 capsules 3 r / day for a month
Phosphogliv	1-2 capsules 3-4 r / day for a month
Legalon	2 tablets 3 r / day for a month

Probiotics

Massive exposure to antibiotics can lead to associated diarrhea and dysbiosis, when pathological bacteria of the intestinal flora outnumber beneficial microorganisms. To prevent such complications, probiotics are included in the chlamydia treatment regimen.

Chlamydia treatment regimen
Bificol	5 doses 3 r / day half an hour before meals for 14-21 days
Lactobacterin	5 doses 3 r / day half an hour before meals for 14-21 days
Bifidumbacterin	5 doses 3 r / day half an hour before meals for 14-21 days
Enterol	1 capsule 2 r / day half an hour before meals

Antibiotics for chlamydia

Antimicrobial drugs are the main tool in the complex treatment of chlamydia. The chronic form of this infection requires the use of not one, but several such drugs at once, most often a combination of 2 drugs of this pharmacological group is used. The dermatovenerologist adjusts the dosage and duration of the course of treatment depending on the patient's response to the antibiotic, the form of the disease, and the dynamics of the course of the disease.

When choosing the most effective drug, the doctor is guided by laboratory test data regarding the sensitivity of a particular pathogen to certain antibiotics. A combination of laboratory culture methods with such a type of research as an antibioticogram will help to more accurately determine this indicator.

Chlamydia treatment regimen
Doxycycline (Dorix, Vibramycin, Vibra-Tabs)	2 r / day 100 mg after meals with uncomplicated chlamydia 10-14 days, with chronic and complicated - more than 14 days
Erythromycin (Erythran, Eracin)	4 r / day 500 mg one hour before meals, the duration of the course of treatment is the same as for Doxycycline
Sumamed (Azithromycin, Zitromax)	1 r / day for 250 mg for 11 days, the full course is 3 g, the first intake is 500 mg, with complicated forms 2 weeks
Lomefloxacin (Levaquin)	1 r / day after meals, 600 mg for 10-14 days, with complicated forms for more than 14 days
Ofloxacin (Floxin, Zanocin, Tarivid, Ofloxin)	2 r / day after meals, 300 mg for 10 days, with a complicated form 14 days
Rovamycin	3 r / day, 3 million IU 2 hours after a meal for 10 days, with a complicated form 14 days
Wilprafen	2 r / day, 500 mg after meals for 10-12 days, with a complicated form 14 days
Pefloxacin (Abaktal)	2 r / day, 400 mg with meals for 10 days, with a complicated form 14 days
Ciprofloxacin (Tsifran, Tsiprobay, Tsiprinol, Tsiprolet)	2 r / day, 500 mg for a week
Levofloxacin (Nolitsin, Norbactin, Urobacid)	2 r / day, 400 mg for 10 days

Chlamydia treatment regimen

Complex therapy of uncomplicated chlamydia is carried out according to the following scheme:

• Preparation takes place within a week. This stage includes immunocorrection (if necessary with a reduced immune status) with Polyoxidonium or Amixin, vitamin therapy with multivitamin complexes, vitamin E, systemic enzyme therapy with Wobenzym, Trypsin. Also, local treatment of manifestations of chlamydia is used: microclysters with Chlorhexidine solution, baths and installations with medications;
• Basic treatment is carried out within 2 weeks with antibiotics, antifungal drugs, if necessary, digestive enzymes (Mezim, Festal, Pancreatin). You can carry out basic treatment, combining it with the first stage of therapy;
• Recovery - lasts for 2 weeks. During this period, the balance of the intestinal microflora with probiotics is restored. According to indications, hepatoprotectors and physiotherapy procedures are used.

Treatment regimen for chronic chlamydia

The choice of treatment tactics for this form of the disease depends on which subspecies of the pathogen caused the infection, and to what extent the clinical signs of chlamydia are manifested.

If chronic chlamydia is atypical, accompanied by complications such as inflammation of the structures of the male genital organ or pathological processes in the pelvic organs in women, the following therapeutic scheme is used:

• Basic treatment is taking drugs from the group of antibiotics, vitamins, antioxidants, immune drugs. 6-7 days after the start of antibiotic therapy, systemic enzymes and antifungal agents are added to the chlamydia treatment regimen;
• Recovery period - hepatoprotectors are used to restore liver function, physiotherapeutic procedures can be used additionally: exposure to ultrasound, laser and magnetic waves. Baths with Chlorhexidine or Perftoran solution are also applied topically.

Treatment regimen for sluggish chlamydia

• Preparation - therapy with enzymes, immunomodulators for 2 weeks, the use of topical agents.
• Basic treatment - even before the end of the first stage, 7 days after its start, the patient begins taking antibiotics, antimycotic drugs, multivitamin complexes and antioxidants.
• Recovery - to normalize all body functions, hepatoprotectors, probiotics, antioxidants, hyaluronidase derivatives (Longidase), physiotherapy procedures, and preparations for local treatment are used.

The use of the above treatment regimens for chlamydia will be successful if certain conditions are met:

• The use of drugs that penetrate the cell barrier and have high activity against pathogens;
• Taking into account the clinical picture and the stage of the inflammatory process: acute, latent, subacute, torpid, as well as the period that has passed since the introduction of the infection: fresh infection, chronic form;
• The duration of the course of treatment is not less than 2-3 weeks to cover 6-7 life cycles of the pathogen, which are 2-3 days.

With this chlamydia, it is unacceptable to engage in self-diagnosis and self-medication. In order not to harm health, you need to follow the recommendations of a dermatovenerologist and strictly adhere to the prescribed treatment regimen.

The author of the article: Lapikova Valentina Vladimirovna | Gynecologist, reproductologist

Education: Diploma in Obstetrics and Gynecology received at the Russian State Medical University of the Federal Agency for Healthcare and Social Development (2010). In 2013 completed postgraduate studies at N. N. N. I. Pirogova.