Klebsiella Ozeny
Botanical characteristics of Klebsiella Ozena
Klebsiella ozeny belongs to the species of facultatively anaerobic gram-negative opportunistic bacteria, which look like thick short sticks in the shape of an ellipse. The size of microorganisms does not exceed a few micrometers. These bacteria are in a stationary state, do not form spores, and have characteristic capsules. Capsules give Klebsiella stability, protecting against adverse environmental influences. Thanks to the capsules, these bacteria have a unique opportunity to survive for a long time in water, soil, on the surface of various objects in closed rooms.
Enterobacterium Klebsiella feels great in dairy products, multiplying both at room temperature and at "minus" (for example, in the refrigerator).
In the process of heating to 65 ° C Celsius, the death of microorganisms occurs within an hour.
Klebsiella got its name from the famous German microbiologist Edwin Klebs (1834-1913).
Klebsiella classification
The classification of modern scientists classifies the genus klebsiella into the family of "enterobacteria" (from the Latin enterobacteriaceae), the class "gamma-proteobacteria", the type of "proteobacteria", the kingdom of "bacteria". Klebsiella belongs to coliform bacteria.
The genus of Klebsiella includes the following species: - Klebsiella ozena; - Klebsiella pneumonia; - Klebsiella rhinoscleroma; - klebsiella oxytoca; - klebsiella ornithinolytica; - klebsiella planticola; - klebsiella terrigena.
Klebsiella ozeny and the fetid coryza
In 80 percent of patients with ozena, or "fetid rhinitis", which is characterized by atrophy of the mucous membranes and walls of the nasal cavity, Klebsiella ozena, formerly called "Ozena stick" or "Abel-Levenberg's stick", was found. In case of ozena disease, a specific secret is secreted in the nasal cavity, which, when dried, turns into crusts with a very unpleasant odor. These crusts tightly clog the mucous membranes, making it difficult for the patient to breathe through the nose. In addition, Klebsiella ozenes provoke other chronic diseases that affect the trachea, larynx and pharynx. The course of the disease is complicated by the appearance of a liquid secretion with a repulsive odor.
Treatment of Klebsiella infections
In the treatment of Klebsiellosis, some types of antibiotics have been effective for a long time: aminoglycosides, ampicillin, chloramphenicol, nifuroxazide, rifaximin, tetracyclines. But recent studies have shown that there are widespread strains of Klebsiella that are resistant to antibiotics. Today, drugs are popular, the active substance of which is the following types of bacteriophages: "Bacteriophage Klebsiella pneumonia" and "Bacteriophage Klebsiella polyvalent" (purified liquid), a combined preparation pyobacteriophage with the trade name "Piobacteriophage complex liquid" (otherwise - "pyopolyphage", "polyvalent pyobacteriophage, "Sextaphagus"). These drugs selectively act either only on Klebsiella, or on a whole complex of bacteria, if these are combined bacteriophages. They have no contraindications for use,but have a significantly lower degree of effectiveness compared to antibiotics, including in the treatment of ozena.
Bacteriophages "Bacteriophage Klebsiella pneumonia", "Pyobacteriophage polyvalent purified liquid" and "Bacteriophage Klebsiella polyvalent" are recommended for use by order No. 231 of 9.06.2003 of the Ministry of Health of the Russian Federation "Protocol for the management of patients. Intestinal dysbacteriosis "with a significant progression of the number of Klebsiella pneumonia.
The drug "Bacteriophage" should be taken three times a day, one hour before meals, strictly on an empty stomach. The permissible single and daily dose of the drug depends on the age of the patient.
Article author: Mochalov Pavel Alexandrovich | d. m. n. therapist
Education: Moscow Medical Institute. IM Sechenov, specialty - "General Medicine" in 1991, in 1993 "Occupational Diseases", in 1996 "Therapy".
