Mycoplasma Hominis In Children

2024 Author: Josephine Shorter | [email protected]. Last modified: 2023-12-16 21:43

Mycoplasma hominis in children

Mycoplasmas are present in the body of women, under certain conditions, mainly during inflammatory processes in the genital zones, they cause infectious diseases of the urinary tract and genital organs. Hominis bacteria are a common cause of chorioamnionitis, pyelonephritis, and postpartum infections. It is not surprising that these microorganisms get on the skin, mucous membranes, in the stomach of newborns.

They cause the development of various pathologies. The consequences of mycoplastosis in infants can be: chronic meningitis and ventriculitis, an abscess of the scalp, wound infection, brain abscess, lymphadenitis, pericardial effusion and the presence of pyogenic microorganisms and their toxins in the blood.

Some time after birth, newborns develop an infection not only in the genitourinary organs. Children with immunodeficiency suffer from empyema and meningitis, bacteremia, peritonitis, soft tissue infections, arthritis, endocarditis. Experts believe that an important risk factor is the lowered content of immunoglobulins in the child's blood (hypogammaglobulinemia).

The perinatal form of infection (from the mother) threatens the development of thrush, poor healing of the umbilical wound. Children, often premature, have breathing disorders and pathological jaundice. Fetal death during the prenatal period is possible. The generalized form affects the cardiovascular and nervous systems, musculoskeletal functions, and skin.

Therefore, children born with such a pathology have a low survival rate. Mycoplasma is the causative agent of a rather complex infectious disease; it multiplies well in the human body. Babies are not only infected during childbirth from an infected mother. The disease spreads through objects (toys, clothes), in which case the bronchi, lungs, pharynx, nose, eyes and genitourinary system are affected.

The severity of a child's course depends on how much the young child is protected by the immune system. Lowered immunity suggests a complex disease process. Mycoplasmosis develops in the pulmonary (respiratory) or urogenital forms, their manifestations are different. The pulmonary form of mycoplasmosis affects the respiratory system, leads to certain changes in the cells of the lungs, causing their destruction.

The disease is acquired by airborne droplets, when the hands of babies in groups of kindergartens come into contact. The first manifestations are an increase in body temperature up to thirty-eight degrees, burning sensation, hyperemia in the pharynx and oral cavity, nasal congestion. In the absence of timely treatment, pneumonia develops. Symptoms are similar to those of the flu, but last long enough.

n

A common symptom of an ailment is a painful and prolonged cough that lasts more than two weeks. A child can cough constantly, according to the experience of doctors, it is known that mycoplasmosis is provoked by bronchitis, bronchial asthma and tracheitis. Urogenital or genitourinary mycoplasmosis consists in inflammation of the urinary organs, the child receives such infection only from the mother during childbirth.

During the diagnostic process, mycoplasma hominis can be determined using blood agar. Standard liquid media (blood culture) are also used. If conventional methods of identifying the pathogen are not effective, a special request for research is made. In the definition of this disease, polymerase chain reaction (PCR) is used, which indicates the presence of DNA of the pathogen in the urine, the culture method, the method of processing paired sera, immunofluorescence (RIF).

When the central nervous system (CNS) is affected by mycoplasmosis, recovery is usually slow, in some cases complications, up to death, are observed. Treatment of the disease is carried out using the drug erythromycin, tetracycline and doxycycline. The positive effect occurs when taking clarithromycin and azithromycin, produced in the form of suspensions.

These funds are well tolerated, practically have no side effects on the work of the gastrointestinal tract. The duration of treatment is approximately 14 to 21 days, it all depends on the choice of antibiotic therapy option and the individual characteristics of the child's body. Modern developments in medicine allow the use of unique methods of treatment:

• extracorporeal immunopharmacotherapy is prescribed, taking into account the peculiarities of the pathogenesis of mycoplasma infection, the intracellular pathway of microbial reproduction and parasitism, the ability to suppress the functional activity of the immune system. This method restores the immune system, reduces the activity of the infectious process.
• Autoplasma cryomodification technologies help to remove autoaggressive antibodies from the body and can quickly eliminate the development of autoimmune complications of mycoplasma infection.

Article author: Mochalov Pavel Alexandrovich | d. m. n. therapist

Education: Moscow Medical Institute. IM Sechenov, specialty - "General Medicine" in 1991, in 1993 "Occupational Diseases", in 1996 "Therapy".